Unlike most other products in your bathroom, you'll notice all of our products have an expiration date. That's because these products are unpreserved. Preservatives can prevent bacterial growth, so they are not compatible with the Ammonia-Oxidizing Bacteria in the Mist.
The Mist will keep its potency for 6 months in the fridge (opened or unopened) or 4 weeks at room temperature (opened or unopened).
By refrigerating, you extend the life of the bacteria, but if you are moving the bottle in and out of the fridge, it's hard to say how long they will retain activity—somewhere between 4-8 weeks and the expiration date marked on the bottle. Taking the Mist out of the fridge for 24 hours once in a while, and then putting it back, shouldn't make much difference to its shelf-life.
The Cleanser does not contain live bacteria, and is completely sterile until your first pump. Once you begin using your Cleanser, it will last for 8 weeks.
The Shampoo and Moisturizer do not contain live bacteria, and are completely sterile until your first pump. Once you begin using your Shampoo or Moisturizer, they will last 6 months from the first pump.